PFAS: A Review of the State of the Art, from Legislation to Analytical Approaches and Toxicological Aspects for Assessing Contamination in Food and Environment and Related Risks

More than 7000 synthetic compounds known as per- and poly-fluoroalkyl substances (PFAS) are applied to food packaging other materials provide fat, fire, and/or water resistance properties. These have exceptional environmental stability persistence due the strong C-F chemical bond, earning them moniker “forever chemicals”. Emission of PFAS from industrial waste leads water, air, soil contamination. Due this ubiquitous nature, combined with fact that in humans carcinogenic reprotoxic effects cause vaccine depression immunity system, may constitute a major threat human health. For reason, attention scientific community control bodies is increasing consequence legislation literature on constantly evolving. This review aims comprehensive overview state art about current addressing PFAS; targeted screening method for identification, detection quantification toxicity contamination matrices contact matrices. A latest research recent developments will insights into understanding its health implications. Moreover, it serve valuable reference further studies related could help informing future policy decisions.